Guesthouse vacation rentals in Jefferson County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Jefferson County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Jefferson County guesthouse rentals
Family-friendly guest house rentals
Guesthouse
4.95 out of 5 average rating, 63 reviewsRetro Chic Private Getaway in the Highlands.
Guesthouse
4.94 out of 5 average rating, 65 reviewsYoga Barn with 90’s Loft Bedroom
Guesthouse
4.88 out of 5 average rating, 60 reviewsThe Waterfall Place, Suite and Walkout!
Guesthouse
4.96 out of 5 average rating, 52 reviewsBourbon Country/ Derby Guest House
Guesthouse
4.93 out of 5 average rating, 293 reviewsCharming Carriage House with 2 private baths.
Guest house rentals with a patio
Guesthouse
5 out of 5 average rating, 10 reviewsHoosier Cottage: So. Indiana
Guesthouse
4.88 out of 5 average rating, 16 reviewsCozy Tree-Lined Carriage Studio w/ games!
Guesthouse
5 out of 5 average rating, 9 reviewsCountry 1 bedroom guesthouse with heated pool
Guesthouse
5 out of 5 average rating, 3 reviewsLots of cozy and fun space!
Guesthouse
4.9 out of 5 average rating, 63 reviewsModern Guesthouse overlooking Ohio River
Guesthouse
4.95 out of 5 average rating, 19 reviewsThe tiny Walnut in Beechmont
Guesthouse
4.89 out of 5 average rating, 76 reviewsChic Derby stay minutes from Churchill Downs!
Guest house rentals with a washer and dryer
Guesthouse
4.98 out of 5 average rating, 84 reviewsHighlands Carriage House - Deer Park
Private room
5 out of 5 average rating, 6 reviewsLewis & Clark Trail Guest Suite
Guesthouse
5 out of 5 average rating, 4 reviewsDeaconessGuesthouseUnit2*Pet*Hot Tub*Lux Amenities
Guesthouse
5 out of 5 average rating, 48 reviewsNew custom guesthouse | Free parking | Sleeps 4
Guesthouse
5 out of 5 average rating, 6 reviewsPrivate 3BR luxury apartment
Guesthouse
5 out of 5 average rating, 60 reviewsLavish church suite with choir loft
Guesthouse
5 out of 5 average rating, 3 reviewsDeaconessGuesthouseUnit4-Pets-Firepit-Waterfront
Destinations to explore
- Guesthouse rentals United States
- House rentals United States
- House rentals Cincinnati
- Guesthouse rentals Louisville
- House rentals Louisville
- House rentals Lexington
- Guesthouse rentals Lexington
- Guesthouse rentals Kentucky
- House rentals Kentucky
- Condo rentals Jefferson County
- Family-friendly rentals Jefferson County
- Rentals with breakfast Jefferson County
- Private suite rentals Jefferson County
- Rentals with a fireplace Jefferson County
- Rentals with a fire pit Jefferson County
- Rentals with lake access Jefferson County
- Monthly Rentals Jefferson County
- Waterfront rentals Jefferson County
- Rentals with a washer and dryer Jefferson County
- Townhouse rentals Jefferson County
- Rentals with a patio Jefferson County
- Rentals with an EV charger Jefferson County
- Kid-friendly rentals Jefferson County
- Loft rentals Jefferson County
- Cottage rentals Jefferson County
- Pet-friendly rentals Jefferson County
- House rentals Jefferson County
- Rentals with a kayak Jefferson County
- Apartment rentals Jefferson County
- Fitness-friendly rentals Jefferson County
- Rentals with outdoor seating Jefferson County
- Rentals with pools Jefferson County
- Rentals with a hot tub Jefferson County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom